Preclinical Pathology Services
Connected-Pathology is an end-to-end pathology service provider that can take your research from necroscopy to storage with convenient entry and exit points to suit your needs.
Simplify your workflow with C-Path
Centralize your pathology services:
For convenient and effective results, Connected-Pathology brings your pathology needs together. Streamlining your projects with the help of our expertise will result in more time and resources for progression.
Flexible entry and exit points:
Only pay for the services you need with our fully customizable workflow. We can accommodate your study needs and offer scalable solutions for a variety of study types.
Necropsy
Grossing
Embedding
Staining
Scanning
Digital Storage
Physical Storage
Our Services
Histology
Routine H&E stainings seamlessly integrated into preclinical workflows
Immunohistochemistry
Full Roche library of antibodies for specific target antigens
Special Stains
Identification of particular cells, tissue structures, and microorganisms
Physical Storage
Archiving slides in secure and regulated storage conditions
Histology
Examples of just some of the readouts we provide include degeneration, morphology, toxicology, efficacy, and semi-quantitative results using H&E staining. Enhanced by the efficiency of digital workflows and automation, Connected-Pathology can improve turnaround times for your diagnostics.
We offer flexible entry and exit points and can provide pathological services on already prepared slides or from slides prepared directly through our Connected-Pathology facilities.
IHC
Connected-Pathology provides an extensive portfolio of IHC staining options and has the facilities and in-house knowledge to develop, optimize and validate additional antibodies for your research.
Using their preclinical expertise our pathologists will consult with you on which IHC markers will be the most valuable for your study and can provide information on the best way to collect and fixate your specimens for the best IHC staining outcomes.
For a full list of antibodies use the link below.
Special Stains
Special Stains, when implemented correctly, can give deeper insights into your research. Our team of experts will guide you through the most appropriate staining options that can provide more detailed and meaningful results to your study.
We offer a comprehensive list and have the facilities and expertise to perform additional staining requests where necessary.
Currently Available:
- Alcian blue
- Congo Rood
- Elastine = EVG
- Giemsa
- GMSII
- Gram
- Iron
- PAS
- PAS-Diastase
- Reticuline
- Sirius Red (PSR)
- Trichroom
- ZN
Physical Storage
With secure and environment controlled storage facilities for both blocks and slides, Connected-Pathology can accommodate both long and short term storage options.
Coupled with simple recall procedures and swift transport possibilities. Storing your specimens with Connected-Pathology provides a convenient solution for ongoing research and centralization of your data.
Digital Storage
Secure archiving and easy retrieval of raw images and analyses data
Cytology
Examination of samples collected typically from body fluids or scrapes
Protocol Optimization
Efficient and cost-effective approach to pathology and troubleshooting
Scientific Advisory
Setting up preclinical pathology analyses with expert support
Digital Storage
With SSD and tape storage options Connected-Pathology offers flexible time storage possibilities for any study.
Our digital pathology viewer, currently being optimized, will allow secure access to your data for spontaneous and collaborative analyses of your high-resolution images.
If you want to be updated on the progress and development of our LIS and viewer technology sign up here
Cytology
Cytodiagnostics can provide insights into malignant or premalignant lesions and can be performed on a large number of tissue types and body fluids.
At our Connected-Pathology facilities, our board-certified pathologists can provide comprehensive analyses of gynecological, non-gynecological, and fine needle aspiration (FNA) samples.
Protocol Optimization
Workflow management is key to achieving improved turnaround times while maintaining a high standard of quality.
Our experienced Roche-trained laboratory technicians can help enhance your current workflows or guide the development of new protocols for your specific antibody needs.
Scientific Advisory
Combining our in-house expertise and thorough industry research we provide strategic and valuable advice on the improvement of your study design. Providing lean and cost effective studies, we aim to create high value results for your ongoing projects.
Through ongoing support and collaboration, we maintain a customer focused approach and can consult on study feasibility and provide appropriate alternatives at any part of your research.
Enhance your drug development
Connected-Pathology offers customized packages to suit your project needs. With multiple entry and exit points you only pay for exactly what you need to streamline and enhance your project with a validated workflow. Our expertise covers the entire process and supports your project from start to finish.
Board certified pathologists
Your pathology support specialized in toxicology, molecular pathology, and animal models of human diseases
Rich staining portfolio
Routine hematoxyline and eosin (H&E) staining, immunohistochemistry, in situ hybridization, and special stains
Scalable packages
Every project is different, and we accommodate that. Our pay as you go principle ensures you only pay for the services you need when you need them
FAQ
What type of preclinical studies benefit from histopathology services?
Pathology workflows can be part of different kinds of preclinical studies, such as:
- Animal models of human disease
- Non-GLP toxicity, safety, and efficacy
- Medical device testing
- Target animal safety (TAS)
We regularly contribute to drug discovery and development pipelines in therapeutic fields including oncology, nephrology, cardio-metabolic, and neurology.
What type of tissues do the histopathological assessments cover?
We frequently receive samples from a variety of tissues including breast, kidney, and brain, and can customize our methods to optimally suit the tissue in question. Fluids can be processed to FFPE blocks or thin layer slides
- Neuroendocrine pathology
- Bone and Soft Tissue Pathology
- Breast Pathology
- Cardiovascular Pathology
- Dermatopathology
- Head nad Neck (ENT)
- Gastrointestinal Pathology
- Genitourinary Pathology
- Gynecologic Pathology
- Hematopathlogy
- Neuropathology
- Obstetric and Perinatal Pathology
- Pulmonary Pathology
- Renal Pathology
Do you only work with typical laboratory animals like rats and mice?
We regularly perform pathological analyses not only for typical laboratory animals but also poultry and larger animals like cows or horses. Our workflows are also suitable for non-human primates (GLP) rabbit, sheep, goat, minipig, broilers, etc.
Do you provide quantitative analyses?
Yes. We offer tissue segmentation, cell counting, cell clustering, among other quantitative image analyses which can be customized depending on your research question. Our AI-driven and automated workflows under development will become particularly valuable assets for quantitative analyses in the near future.
What kind of human disease subspecialties are covered within the Connected-Pathology team?
Connected-Pathology is always growing and continually adding sub-specialties to our capabilities within the field of pathology however we currently offer expert and in-depth analysis within the following human diseases:
- Degenerative diseases
- Oncology diseases
- Metabolic diseases
- Infectious diseases
How do we rationalize the cost of your study?
With our in-house expertise and guidance, we can facilitate flexible study designs to suit your research goals and budget.
The Connected-Pathology team can be as involved in your project as is needed. We calculate our costs based only on the services you need, combined with the size of your project.
Our two step design process is aimed at guiding a cost efficient workflow that draws on the knowledge of our pathologists. This process helps you achieve the most accurate outcomes with as little expenditure as possible.
If however, you already have your target antigen in mind? We can validate your antibody in-house or if we already have it available, can begin your study with IHC staining methods for in-depth results on your specimens. These are all options that vary in cost but are dependent on the services you need to be fulfilled.
For a quote or further questions please reach out to us at info@c-path.be
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Curious about pricing and where our digital services can step in? Reach out today – We’d be happy to answer any questions.
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