Histopathology Techniques: Evaluation of Therapeutic Antibodies Ex Vivo in Neurodegenerative Disease Research
The therapeutic potential of antibodies was discovered based on experiments evaluating serum from animals exposed to attenuated forms of pathogens. Since then, an enormous progress has been made in our understanding and designing of therapeutic antibodies or...
Histopathology as a Quick, Effective and Complimentary Target Identification and Validation Method
Target identification and validation represents a key first preclinical drug development phase leading up to clinical trials. In this case, target is used as a broad term, and represents a range of biological entities, including proteins, genes and different forms of...
Toxicologic Pathology: How to Get the Most Value out of Your Outsourced Toxicology Studies
As the name indicates, the field of toxicologic pathology integrates the disciplines of pathology and toxicology. In the preclinical field, toxicologic pathologists integrate these two fields in an experimental setting to evaluate the safety of different therapeutic...
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